Longevity is not only about knowing your biology. It is about acting on it. Vitality is River's intervention layer — evidence-based therapies and curated products that translate your biological data into measurable outcomes.
River's biological stack and diagnostic suite tell you precisely what your body needs. Vitality is how you give it. Every product and therapy within Vitality is selected because it is backed by clinical evidence, because it connects directly to what your biology has revealed, and because it meets River's standard of quality — which is not the market standard.
A principle River will not compromise on: Every Vitality product and therapy at River is informed by your individual biological data. Nothing is prescribed or recommended generically. If your metabolomics shows a specific nutritional gap, your supplement protocol addresses that gap — not a population average. If your genomics reveals a drug metabolism variant, your physician knows before prescribing. This is personalised medicine, not personalised branding.
Bypassing the digestive system entirely — for bioavailability no oral supplement can match.
Intravenous therapy delivers nutrients, cofactors, and therapeutic compounds directly into the bloodstream — achieving tissue concentrations that oral administration cannot reach. At River, every IV protocol is preceded by a biological assessment and administered under physician supervision.
NAD+ Infusion
Cellular energy & longevity
Nicotinamide adenine dinucleotide — a coenzyme central to cellular energy production and DNA repair that declines sharply with age. IV NAD+ restores levels that oral supplementation cannot reliably achieve, supporting mitochondrial function, cognitive clarity, and metabolic recovery.
Glutathione Infusion
Master antioxidant
The body's primary antioxidant and detoxification molecule — produced endogenously but declining with age, stress, and illness. IV glutathione supports liver detoxification, reduces oxidative stress, and has documented benefits for skin health, immune function, and neurological protection.
Vitamin C High-Dose
Immune & connective tissue
At high intravenous doses, Vitamin C acts as a pro-oxidant in cancer-adjacent cells while supporting collagen synthesis, immune activation, and adrenal recovery in healthy tissue. The therapeutic range achievable via IV cannot be reached through any oral dose without causing gastrointestinal intolerance.
Myers' Cocktail
Micronutrient replenishment
A clinically established combination of magnesium, B vitamins, Vitamin C, and calcium — addressing the micronutrient deficiencies most commonly identified in metabolomic profiling. Recommended when River's metabolomics data shows specific deficiency patterns.
Amino Acid Complex
Muscle & metabolic support
Essential and conditionally essential amino acids delivered intravenously to support muscle protein synthesis, metabolic rate, liver function, and neurotransmitter production — particularly relevant for individuals in active body composition programmes or post-surgical recovery.
Portfolio expanding
More protocols coming
River's IV therapy portfolio is built iteratively — each protocol added only after it meets River's evidence and safety standard. Phosphatidylcholine, Alpha-lipoic acid, and targeted hormonal support protocols are currently under clinical review.
All IV therapies at River are administered under physician supervision, preceded by relevant biological profiling, and dosed according to individual biological data — not population protocols. River does not offer walk-in IV therapy.
Not what the market sells. What your biology actually needs.
The supplement industry is one of the most noise-filled markets in health. River cuts through it with a simple principle: every supplement we recommend must be supported by peer-reviewed evidence for your specific biological gap, must meet pharmaceutical-grade quality standards, and must be selected for you — not for the average person.
Category 01
Genomics-Informed Protocols
Supplement recommendations built directly from your genomic data — addressing the specific nutrient metabolism variants, absorption differences, and genetic predispositions your genome reveals. Your MTHFR status, your Vitamin D receptor variants, your omega-3 metabolism — all of it informs the protocol.
Category 02
Metabolomics-Guided Nutrition
Nutritional supplements selected to address the specific deficiencies and metabolic gaps identified in your metabolomic profile. Where a standard panel might suggest Vitamin D deficiency, River's metabolomics shows which co-factors are limiting absorption — and the protocol addresses both.
Category 03
Longevity Foundations
A curated core stack for cellular health, mitochondrial function, inflammation modulation, and cognitive protection — selected from the compounds with the strongest longevity evidence base. Includes NMN, Resveratrol, Spermidine, Berberine, and others reviewed against current literature.
Category 04
Microbiome Support
Probiotic, prebiotic, and postbiotic protocols matched to the specific microbial imbalances and deficiencies identified in your microbiome analysis. Not a generic probiotic from a pharmacy shelf — a targeted intervention based on your actual gut ecosystem data.
Category 05
Hormonal Support
Evidence-based supplementation for hormonal balance, adrenal support, and endocrine function — selected in response to the hormonal profiling in your biomarker panel. Every recommendation made with awareness of your complete hormonal picture, not a single isolated marker.
Coming soon
River-Curated Supplement Range
River is developing a curated supplement range — formulated to pharmaceutical standards, validated against the biological data River collects, and available exclusively through River's clinical network. Launching in a future phase.
River's supplement principle: We do not recommend supplements we cannot justify with evidence, and we do not benefit from recommending more than you need. Every protocol is reviewed periodically against your evolving biological data — and adjusted or discontinued when the data changes.
Physician-supervised. Genomics-informed. Individually dosed.
One of the most underappreciated facts in medicine is that most drug prescribing is done without knowledge of how the patient's genome processes that drug. The same dose of the same medication can be therapeutic in one person, ineffective in another, and dangerous in a third — based entirely on genetic variants in drug metabolism enzymes.
Real-world example · Pharmacogenomics
GLP-1 Weight Loss Medications & Pancreatitis Risk
GLP-1 receptor agonists — the class of medications used for weight management including drugs like semaglutide — have transformed metabolic medicine. But they carry a known risk of pancreatitis in certain individuals, a risk that is substantially influenced by genetic factors.
A PGx test identified elevated pancreatitis risk in patients prescribed GLP-1 medications — enabling the treating physician to modify the prescribing decision, adjust dosing, and implement monitoring protocols before any adverse event occurred. For several patients, this information changed the treatment plan entirely.
Speciality pharma portfolio includes
Physician-Supervised Programmes
Metabolic optimisation programmes, hormonal recalibration, peptide protocols, and unique pharmaceutical-grade products — all selected for their evidence base, all administered under physician oversight, and all informed by the biological data River has collected about the individual patient.